Time is flying, and I have been experienced as a 2-year Editor-in-Chief for Journal of Molecular Cell Biology (JMCB) since 2011. As a new journal issued in October of 2009, JMCB aims to be a prestigious journal with its unique spirits in scientific communities. The first mission of JMCB is to publish primary research papers with findings of unusual significance and broad scientific interest. The first issue of the journal reports an interesting work on generating induced pluripotent stem (iPS) cells of pig for the first time in the world (Wu et al., 2009), which become the most cited paper of the journal. Since then, I have worked hard with the helps of editorial board to pursue this goal. We have published many interesting research papers within recent 2 years. For example, Dr Jiang and colleagues showed that the 2009 pandemic H1N1 strain can induce apoptosis in epithelial cells of the human respiratory tract, incorporating the concept of apoptosis with the pathogenesis of H1N1 influenza virus (Yang et al., 2011). The relationship between metabolic states and pluripotent states is an …